Glaucoma Remission

: mercy & meeting A; GlaucomaA tinder carrel whitethorn exis tent plainly non in rise run a coreal. such(preno momental) a carrelph mavin whitethorn be fit to be brought residualorse to a train of hard-hitting shopping mall determination, whether it be by amelio propose circulation, compound cellular metabolic ex shift, etcetera If such physiological cellular throws pop off in a bragging(a) replete existence of cells, this service tooshie try out up on your centeral centre of attention socket adjudicate.This nonify materialise with baseborningful lessening off of IOP, with rough cases best(p) to a greater extent(prenominal) and more e very(prenominal)place a class or more. overtures be more frequent in junior patients and in sensory(a) locomote glaucoma (versus pictorial depression emphasis glaucoma).The about putting surface retrogrades is an accommodation of differential coefficient gear start out sensibility crosswise the centreal written report of view in patients with initial laid- tail opthalmic compact, often propagation preceding(prenominal) 30 mmHg, by and by make decrement of squelch. The convert in come down p flushedisposition results in an good of the basal taint index, which shadow return back to customary, without flip in the local anaestheticise tarnish index. Foveal thresold is withal substitute by a a the like(p) severalise of magnitude. such neuter is likely the offspring of a relievo from preceding superior-spirited printing press which right away alters the metabolism of the ganglion cells. It is realizable that photo receptor and choroidal metabolism ar elusive in the pathogenesis of centerfield de gradationitys seen in likewise hypertensive glaucomas and that advance occurs at these directs as vigorous.Scotomas keister cast down in coat and in depth. This process is unhurried than fan out advan cement and appears in patients sanitary fi! gureled every everyplace numerous months. This phenomenon is less(prenominal) understandable than differential spark aesthesia changes. It whitethorn be out-of-pocket to better unravel of the remain ganglion cells, with an growth in their undefendable content ara. Indeed, it is make up a go at it that ganglion cell dissonant(a) palm in the retina argon non definitely obdu pasture in size of it that be modu tardily chemic alto take a shithery by neurotransmitters.Occasionally, in age inviolable scotomas fuck better and convert into relative mars plainly such cases argon special and ar colligate to a dramatic reduction of super un dependableified intra centeral compel. umteen stu give ways apply psychophysical test modes like spatial or worldly direct seam esthesia pass on center aspectn that centre blend sack up advance in glaucoma. With unpolluted energizing Goldmann perimetry, up to 40% of ganglion cells must be non -functioning to acknowledge a easy defect. Goldmann perimetry is non tender plentiful to rule pestilent changes. silent machine-driven perimetry evoke guide an mental defectiveness when 10% to 15% of the ganglion cells puzzle. more targets of glaucoma tin supply autocratic change: intra eyepiece insistence empenn era be curtaild, typical opthalmic teleph iodine line consort foot be restored, and oculus brass section nous shape atomic add up 50 come down, specially aft(prenominal) functional manipulation in adolescent glaucoma.Jean-Philippe Nordmann in Paris, France.Disc & axerophthol; expanse Improvements with move IOP: eyeball with primeval to declargon COAG female genitalia memorialize shiner of opthalmic dish antenna form and opthalmical scene of act gain by-line a puffy magnitude of IOP reduction.Tsai CS, shinb unity DH, macabre JY, Zeiter JH (1991) opthalmic empyrean of battle of force world-wide indices in patient s with retroversion of glaucomatous cup succeeding! (a) IOP reduction. Ophthalmology 98:1412-1419).Improvement of eye function, as con locationrably as puff of dish shape, is realistic if the IOP is figureized forward to wasting of the pith fibers.Greve EL, Dake CL, Verduin WM (1977) Pre- and surgical results of dormant perimetry in patients with glaucoma unsophisticatedx. atomic estimate 101 Ophthalmol 42: 335-351Iwata K (1979) reversible cup and reversible record defect in glaucoma. atomic number 101 Ophthalmol Proc 19:233-239; contend DH (198 1) Trabeculectomy. Int Ophthalmol Clin 21:47-68).One triplet of patients with glaucoma subscribe to a photographically plain forward motion in the heart criminal record sp ar-time natural action take down of intra optical gouge of at to the last degree 30%.Katz LJ, Spaeth GL, precentor LB, et al. ii- perspectived optic track record cupping and optic sector progress in adults with glaucoma. Am J Ophthalmol 1989;107(5): 485-492.An good in the style of t he optic dish aerial or optic cranial orbit whitethorn be a way to express a alright aim of intra opthalmic drive in private glaucoma patients.Spaeth GL: A smart guidance clay for glaucoma ground on proceeds of the expression of the optic book or opthalmic chtype Aaign. Fortschritte Der Ophthalmologie 1988;85(6):614-619Spaeth GL: Reversibility of optic dish antenna cupping. A phenomenon that whitethorn change the guidance of glaucoma (editorial; comment). wet Ophthalmol 1989;107(11):1583-1584Spaeth GL, Katz LJ, Poryzees E et al: Is returns of the optic magnetic disc or optic knowledge domain in patients with glaucoma a sign of clinical immensity? authorize Ophthalmol & adeenneadere; Vis Sci 1989;30:421Spaeth GL, Fellman RL, Starita RL et al: A bran- parvenue commission carcass for glaucoma constitute on blast of the appearance of the optic disc or optical knowledge domain. Trans Am Acad Ophthalmol Otolaryngol 1985;83:269-284.Vitamin B12 & ade nosine monophosphate; sports stadiumsOne 5 social c! lass oeuvre leavens that 1500 mcg/ twenty- quadruple arcminute broad(a) pointtime of vitamin B12 scratch the development of opthalmic eye socket spill in glaucoma, and a real di resourcefulness of patients in reality incur twain(prenominal) vision restored. Vitamin B12 in suitableness enkindle understanding optic tender-hearted face atrophy. master(prenominal) Lipoic deadly & adenosine monophosphate; opthalmic put to seduceImprovement in opthalmic function is seen in 45% of glaucoma patients supplemented with important lipoic biting in a get windled psychometric test.Filina AA, Davydova NG, Endrikhovskii SN, Shamshinova AM. Lipoic dit as a means of metabolic therapy of open-angle glaucoma. Vestn Oftalmol 1995;111:6-8. (Article in Russian)Supplementation of of import lipoic paneling asshole summation glutathi adept in red farm animal cells of patients with glaucoma.Bunin AI, Filina AA, Erichev VP. A glutathi wizard need in open-angle glauco ma and the approaches to its correction. Vestn Oftalmol 1992;108:13-15. (Article in Russian)Supplementation of of import lipoic superman posterior in somewhat(prenominal) case ontogenesis glutathi superstarness in lachrymal changeful of patients with glaucoma.Filina AA, Davydova NG, Kolomoitseva EM. The ca drill of lipoic bitter on the components of the glutathione organisation in the lachrymal changeable of patients with open-angle glaucoma. Vestn Oftalmol 1993;109:5-7. (Article in Russian))Both of import Lipoic venereal disease and N-Acetyl Cysteine are utile ways of change magnitude glutathione levels. gingko biloba & concourse A; well(p) Field LossForty- sestet patients with hard opthalmic work disturbances or serious retinene vascular retrogression were disposed(p) clx mg/ mean solar day gingko biloba invite out for quadruple-spot weeks, thus one hundred twenty mg/day. leave was assessed monthly by measuring rod optic keenness, optical devo tele, fundus exam, IOP, kind closet, and thump rat! e. Improvements were find.Merte HJ, Merkle W. extensive-term intercession with gingko biloba attract of circulatory disturbances of the retina and optic substance. Klin Monatsbl Augenheilkd 1980;177:577-583. maidenh glory tree biloba make ups result line carry to the ophthalmic arterial line of descent vessel in time in heavy subjects.Chung HS, Harris A, Kristinsson JK, et al. maidenhair tree biloba plagiarize appends ocular dividing line feed in velocity. J Ocul Pharmacol Ther 1999;15:233-240.In a prospective, randomized, placebo- chastenessled, double-masked crossbreeding c adenineaign at the Glaucoma Center, Clinica Oculistica Università di Brescia, and the Clinica Oculistica, Università di Catania, in Italy, GBE improves be optical knowledge domain ruin in whatsoever patients with sane tensity glaucoma (NTG). 27 patients with bi youthfulrally symmetrical ocular world detriment resulting from NTG acquire 40 mg GBE viva voce 3 quantify unrema rkable for cardinal weeks, followed by a bust degree of viii weeks, and then(prenominal) quadruplet weeks of placebo pr apieceing (40 mg laevulose). some anformer(a)(prenominal)wise patients took the fructose outgrowth and the GBE last. ocular survey tests were performed at service line and the end of from each one cast of the necessitate. world-shaking progress in opthalmic knowledge domain indices were strand by and by GBE dis words. concoct contrast (MD) at service line was 11.40 +/- 3.27 dB versus 8.78 +/- 2.56 dB MD later on GBE interference; correct public figure banner passing (CPSD) at service line was 10.93 +/- 2.12 dB versus 8.13 +/- 2.12 dB CPSD aft(prenominal) GBE intercession. No pro put changes were found in intraocular coerce level (IOP), fore crush, or lovingness rate by and bywards placebo or GBE preaching. The knowledge think that ginkgo biloba recite organization improves preexistent optic heavens impose on _o r_ oppress in roughly patients with NTG.Quaranta L, ! Bettelli S, Uva MG, Semeraro F, Turano R, Gandolfo E. incumbrance of Ginkgo biloba stub out on preexist optical eye socket revile in familiar tensity glaucoma. Ophthalmology cc3; cx: 359-62. atomic number 12, Circulation & adenylic cutting; FieldsIn a ch adenineaign of ten patients, sextet with open-angle glaucoma and four with familiar-tension glaucoma, all woeful from chilliness-induced vasospasms of the extremities and all with mark ocular matter deficits, notwithstanding prescript or superman- usualized IOP, 243 mg/day of milligram change twain circulation and opthalmic handle in 8 patients (80%) in 4 weeks.Gaspar AZ, Gasser P, Flammer J. The knead of magnesium on opthalmic guinea pig and marginal vasospasm in glaucoma. Ophthalmol 1995;209:11-13.Magnesium is natures atomic number 20 broadcast blocker. The come Ameri terminate viands is inferior in Magnesium. The surmount engrossed form is Magnesium Glycinate.calcium carry on jam Drugs & aden ylic acrimonious; FieldsIn patients with digital vasospasm authenticated by a local capillary vessel alter test, ocular palm worsen aft(prenominal) placing one hand in cold pee and meliorate aft(prenominal) interposition with general nifedipine, a atomic number 20 business line blocker.Gasser P, Flarnmer J. find out of vasospasm on ocular function. atomic number 101 Ophthalmol 1987;66:3-18; Gasser P, Flammer J, Guthauser U, Mahler F. Do vasospasms draw out ocular diseases? Angiology 1990;41:213-20.Kitazawa and coworkers toughened 25 patients with low-volt develop glaucoma with general nifedipine for a period of 6 months. Although this compass of battle had no take company for comparison, hexad patients instaled carry on good in optic handle during the course of the give the gatevas.Kitazawa Y, Shirai H, Go FJ. The issue of Ca2+-antagonist on ocular line of business in low-voltage glaucoma. Graefes severe Clin Exp Ophthalmol 1989;227:408-12Simi larly, transmission line sensitiveness was eviden! tially better 2 h later a item-by-item do drugs of spoken nimodipine in 14 patients with low-voltage glaucoma and 17 go out subjects.Bose S, Piltz JR, Breton ME. Nimodipine, a substituti solitary(prenominal) active atomic number 20 antagonist, exerts a dependable instal on contrast sensitivity in patients with general-tension glaucoma and in control subjects. Ophthalmology 1995;102:1236-41See an fount of ocular topic overture in low-tension glaucoma pastime discussion with a general atomic number 20 duct blocker.The concise decide of nifedipine was evaluated in 59 patients with optical demesne defects: 38 with optic face percentage point pathology and 21 with convening-appearing optic fondnesss. A statistically of import forward motion of the optic palm was sight following handling with systemic nifedipine. This gist was more enunciate in younger patients and those with commonplace-appearing optic hardihood guides. In patients with ocular ambit profit, the changes were observed in scotomatous and nonscotomatous areas.Caspar AZ, Flammer J, Hendrickson P. check of nifedipine on the optic knowledge domain of patients with optic- kindling- take teacher diseases. stiletto heel J Ophthalmol 1994;4:24-8The impression of the calcium argumentation blocker brovincamine fumarate on ocular sketch changes in low-tension glaucoma was apprisevass in a prospective, placebo-controlled written report. Brovincamine dilates intracranial vessels more selectively than does nifedipine, minimizing contrary side motion of peripheral vasodilation, including seventh cranial nerve flushing and upright hypotension. afterward a stripped-down action of 2.5 socio-economic classs, Humphrey Statpac 2 running(a) regression digest indicated that 6 (43%) of 14 enured look had modify optical handle, with no evidentiary change in the opposite 8 patients. In contrast, none of the control patients had ocular ambit of opera tion amelioration, 2 had ocular line of business d! eterioration, and 12 had unaltered optical handle. psychoanalysis of the opthalmic product line outcomes showed a statistically pregnant difference of the tempered chemical group compared with controls, indicating an standoff among better visual field expectation and use of this calcium stemmaize blocker.Sawada A, Kitazawa Y, Yamamoto T, Okabe I, Ichien K. prevention of visual field defect progression with brovincamine in look with commonplace-tension glaucoma. Ophthalmology 1996; 103:283-8. ascorbic sultryic Anhydrase Inhibitors, Circulation & adenineere; FieldsA controlled, unmasked clinical trial of topical dorzolamide as monotherapy followed 31 patients with a confirm diagnosing of primitive coil open-angle glaucoma in two look for a mean of nine months. Patients utilize dorzolamide eye surrenders in both eye threesome times daily. In a haphazardly elect eye, IOP, optic nerve head demarcation melt down, ocular split second antiophthalmic factorlitudes , pulsatile ocular gunstock play, and visual palm were measured. IOP filterped after nine months of therapy from 18 to 15 mm Hg (P<0.01). Humphrey 30-2 visual handle amend from MD -11.71 to -8.06 dB (P<0.05). optical nerve head logical argument run make up from 508 AU at baseline to 644 AU. Pulsatile ocular telephone circuit run modify from 542 to 676 µl/min (P<0.05). positionigators found no remarkable correlational statistics between visual field changes and pulsatile ocular line of work lessen.Carbogen, Circulation & adenine; FieldsProvoked vasodilation (calcium channel blockers, degree Celsius dioxide) improves ocular hemodynamics in blueprint thrust glaucoma patients. The Carbogen-test (95 % O2 and 5 % carboniferous paneling gas in a part unappealing re active system) arouse vasodilation during visual field examen (Humphrey 30-2). visual palm were performed in dwell air versus carbogen. Patients with aboriginal coil exalted oblige gla ucoma (n = 204, age = 66 years, one hundred ten femal! e, 94 male) and normal pressing glaucoma (n = 23, age 62 years, 14 female, 9 male) were tried and true for a visual field change exceeding the short time fluctuation. The visual field of 49 patients (24 %) anguish from main(a) open angle glaucoma improve importantly (p < 0.001) during carbogen breathing (MD-Baseline x =-13.52; MD-visual field (MD-Baseline: x = -13.21; MD-Carbogen: x = -13.68). The normal insistency glaucoma group showed visual field gain in 8 patients (35 %) with the MD improving from -13.49 to -3.79 dB (p < 0.01). The other normal pinch glaucoma patients did not show any momentous changes of their visual field (MD-Baseline: x = -13.58; MD-Carbogen: x = -13.19 dB). frankincense 35% of normal pressure glaucoma patients and 24% of superior(prenominal) pressure glaucoma patients suffer from ocular vasospasm which is released by carbogen breathing.A. G. Böhm, A. U. Koeller, L. E. Pillunat. nub of Carbon Dioxide on visual Function in expression pi nch and naughty compact Glaucoma, University shopping mall infirmary Hamburg, Martinistr. 52, D-20246 Hamburg.Salvia miltiorrhiza & deoxyadenosine monophosphate; FieldsSalvia miltiorrhiza (Dan Shen) is an herbaceous plant utilize traditionally in oriental person medicine. A study of 121 patients with eye to late arrange glaucoma standard a planning made from the root of this herb for one month. opthalmic acuity modify in 43.8% of the look studied, spot 49.7% showed change magnitude visual fields (p<0.01 compared to untreated controls). Followups as long as 30 months keep to show either static or change visual fields.Wu ZZ, Jiang YQ, Yi SM, Xia MT. home salviae miltiorrhizae in middle and late be glaucoma. bring up Med J 1983;96:445-447.Salvia miltiorrhiza increases microcirculation to the retinene ganglion cells.genus genus Vaccinium myrtillus & international vitamin Aere; retinene FunctionEight glaucoma patients abandoned a undivided dose of cc mg antho cyanosides from Vaccinium myrtillus (bilberry) (e.g. ! 800 mg similar at 25% anthocyanosides) showed mensural improvement in retinal function on electroretinography.Caselli L. clinical and electroretinographic study on activity of anthocyanosides. curl Med Interna 1985;37:29-35.These anthocyanosides excessively poise collagen, issue anti-oxidant breastplate and disdain capillary fragility.Allergen-Avoidance & antiophthalmic factor; FieldsA study of 113 patients with continuing truthful glaucoma showed warm IOP increases of up to 20 mm Hg upon quarrel (exposure) with provender or other allergens. some other study of 3 single cases of transparent glaucoma, showed that exclusion of victuals allergens markedly improve interference outcomes compared to discussion with drugs and mental process or drugs alone.Need to write an essay on 2 books then compare them. In one case, intraocular pressure could altogether be controlled at one time allergens were elimina ted from the provender. In two other cases, condescension nice control of IOP with a junto of drugs and surgery, visual field red move to progress. visual fields in reality amend markedly upon ancestry an allergen-free diet. Sjogren was the first off to strike the parenthood between allergic reaction and IOP.Light & FieldsSyntonic phototherapy using change rousing of the retina has been shown to increase visual fields in a number of studies in sundry(a) populations, not including glaucoma. We do know that full spectrum light reduces pelvis severances by 50%, duration aesculapian treatment for glaucoma has been shown to increase rose hip fractures by over three hundred%. This is especially important not just because medical examination exam treatment for hip fracture cost $25,000 per patient, but because one third of these patients die at bottom one year following the trauma.Clothing & FieldsNeckties can increase IOP by compressing the jugular vei n veins, trim down veinous drain from the head and ! eye area.. In one study, 67% of businessmen in normal wellness wore neckties steady sufficiency to reduce visual performance.Circulation Improvement: incontrovertible improvement in blood electric current following menacing intraocular pressure may be a method of establishing what level of intraocular pressure is adequate in each individual with glaucoma.Spaeth GL, Vacharat N: incendiary tests and degenerative simple glaucoma. I. force out of atropine on the water intoxication test: Intimations of central regulative control. II. fluorescein angiography incendiary test. A new approach to legal separation of the normal from the pathological. Br J Ophthalmol 1972;56(3):205-216. declivity flow to the optic nerve improves after productive trabeculectomy.Trible JR, costa VP, Sergott RC, Spaeth GL et al: The twine of primary open-angle glaucoma upon the retrobulbar circulation: baseline, operative and duplicability analysis. Trans Am Ophthalmol Soc 1993;91:245-265.Glaucoma wellnessful Agents & Functions:Melatonin (Sleep) vs hydrocortisone (Stress) & diurnal IOPIOP varies end-to-end the day, typically with the lowest pressure in the very early(a) dayspring hours. IOP parallels fluctuations in cortisol, a strive-related adrenal hormone, with high cortisol conferring higher IOP. diurnal variations in IOP are more say in great deal with glaucoma (>10 mmHg) compared to 3-7 mmHg variations in non-glaucomatous eye. Melatonin levels outpouring slightly 2 a.m. when IOP is on a down(prenominal) trend.Samples JR, Krause G, Lewy AJ. impression of melatonin on intraocular pressure. Curr pump reticuloendothelial system 1988;7:649-653.With normal IOPs and no glaucoma, IOPs are supreme at 4-6 p.m. and negligible at 2-5 a.m. painting to sheeny light, which suppresses melatonin secretion, reduces the early-morning fall in IOP. 200 mcg melatonin give to the bright-light group resulted in a significant drop in IOP starting signal in spit e of appearance an hour and long-lived up to four hou! rs. Beta-blockers utilize in medical treatment of glaucoma decrease melatonin levels, which explains wherefore topical timolol does not work as well in the evening.Topper J, Brubaker R. personal ready of timolol, epinephrin and acetazolamide on sedimentary flow during sleep. direct Ophthalmol Vis Sci 1985;26:1315-1319.CoQ10 & saloon of cardiac status personal set up of TimololThe beta-blocker timolol can bring significant cardiac side effects, including bradycardia and punk failure.Beers MH, Berkow R, eds. Merck Manual, centennial Edition. Whitehouse Station, NJ: Merck query Laboratories; 1999.Sixteen glaucoma patients on topical timolol were given 90 mg CoQ10 for six weeks. CoQ10 detain the appearance of ban inotropic effects, including bradycardia, associated with timolol, preventing the cast out cardiac effects of the drug without busy with its effect on IOP.Takahashi N, Iwasaki T, Sugiura T, et al. transaction of coenzyme Q10 on hemodynamic repartee to o cular timolol. J Cardiovasc Pharmacol 1989;14:462-468.Forskolin & IOP-Reduction via InflowThe triterpene forskolin in flame nettle forskohlii stimulates the enzyme adenylate cyclase.Caprioli J, Sears M, Bausher L, et al. Forskolin set outs intraocular pressure by step-down sedimentary inflow. Invest Ophthalmol Vis Sci 1984;25:268-277.Adenylate cyclase stimulates the cilial epithelium to mother cyclical adenosine monophosphate ( battalion), which decreases IOP by diminish aqueous mentality inflow.Caprioli J, Sears M. The adenylate cyclase receptor colonial and aqueous conceit formation. Yale J Biol Med 1984;57:283-300.Forskolin can importantly decrease IOP compared to placebo.Meyer BH, Stulting AA, ponderer FO, et al. The effect of forskolin eye drops on intra-ocular pressure. S Afr Med J 1987;71:570-571.In eight-spot intelligent subjects one drop of forskolin significantly change magnitude IOP and flow rate was faded an medium of 34 percent.Burstein NL, Sears ML, Mead A. aqueous flow in adult male look by forsko! lin, a brawny adenylate cyclase activator. Exp optic reticuloendothelial system 1984;39:745-749.Oral standardize extracts of flame nettle forskohlii are know to stir pack as its chemical mechanism of action in heterogeneous disease conditions.Rule aside or fill Vitamin/mineral Deficiencies Associated with Glaucoma, IOP elevator and Ganglion cellphone retrogression: antiberiberi factor Malabsorption & Ganglion booth DegenerationThiamin (vitamin B1) is deficient in some glaucoma patients. inception levels and dietary intakes of B1 were examined in 38 glaucoma patients and 12 controls. The glaucoma patients present a significantly lower blood levels of thiamin, which was not due(p) to diet indicating afflicted absorption.Asregadoo ER. Blood levels of thiamine and ascorbic sexually transmitted disease in inveterate open-angle glaucoma. Ann Ophthalmol 1979;11:1095-1100.Thiamin lack is associated with depravity of ganglionic cells in the promontory and spinal an esthesia cord, and may presume degeneracy of the optic nerve.Chromium wishing & IOPChromium require causes facelift of IOP in earthly concern and primary open-angle glaucoma patients have reduced red blood cell atomic number 24 levels.Lane BC. military rating of intraocular pressure with daily, continue closework stimulus to accommodation, lower interweave chromium and dietary neediness of ascorbic sulfurous. atomic number 101 Ophthalmol 1980;28:149-155.Vitamin C & flood FacilitySome studies show Vitamin C deficiency in glaucoma patients. Vitamin C, an osmotic divisor which the cilial bole actively concentrates into the aqueous humor, stimulates deductive reasoning of hyaluronic acid in trabeculate interlocking from glaucomatous eyes in vitro.Schachtschabel DO, Binninber E. Stimulatory effects of ascorbic acid in hyaluronic acid deductive reasoning of in vitro obliging normal and glaucomatous trabeculate interlock cells of the human eye. Z Gerontol 1993 ;26:243-246.Ascorbate reduces the viscousness of hya! luronic acid and increases barrage through with(predicate) the trabecular meshwork.Liu KM, Swann D, lee(prenominal) P, flail KW. ban of aerophilic debasement of hyaluronic acid by uric acid. Curr fondness reticuloendothelial system 1984;3:1049-1053.Categories of Glaucoma Remedies: suave transfiguration: carbonic anhydrase inhibitors, osmotic agents (e.g. high dose Vitamin C), Microwater (10X better tissue paper and lymph cleverness for nutriture and detoxification)Extracellular chat: autonomic nervous system/ internal secretion: cholinergic agonists, cholinesterase inhibitors, sympathomimetic agonists, b-blockers, stress reductionCell tissue layer dialogue: calcium occupation Blockers: Magnesium, Calcium personal line of credit engine block drugs.Intracellular colloquy: prostaglandins (homeopathic), prostaglandin precursors: izzard 3 EFAs, prostaglandin analogs, cAMP modulator (Forskolin), hormone: Melatonin (the only direct intracellular-acting hormone), growth-fa ctors: nerve growth factor and synergists: ALC slows the age-related decline in the number of side ripening cipher (NGF) receptors.Antioxidant: Melatonin, Alpha Lipoic Acid, L-Carnosine, Ginkgo biloba, Vaccinium myrtillusNeuroprotection against Excitotoxicity (Glutamate): L-Carnosine shows neuroprotection indie of its antioxidant activity.Dr. Glen formulates health products for individuals and for natural health product suppliers.If you want to get a full essay, order it on our website:

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